BT LAB

SKU: BT-AP02064-50ul

IGF-IIR(Phospho Ser2409) Polyclonal Antibody, 50ul

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions| including in the intracellular trafficking of lysosomal enzymes| the activation of transforming growth factor beta| and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however| imprinting of the human gene may be polymorphic| as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Technical Specifications

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, IHC-p, IF, ELISA

Detection Target:IGF2R

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Research Areas:Immunology; Signal transduction; Tags & cell markers

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Reactivity:Human, Mouse, Monkey

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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