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SKU: E-AB-15453_120μL-ES
ABI1 Polyclonal Antibody, 120 μL
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.6 mg/mL
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Calculated Molecular Weight:55kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:55kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200
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Features and Capabilities
Application:WB;IHC
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Research Areas:Cell Biology;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:Abelson interactor 1;Abi-1;Abi1;ABI1;Abl binding protein 4;Abl interactor 1;Abl interactor protein 1;Abl-binding protein 4;AblBP4;e3B1;Eps8 binding protein;Eps8 SH3 domain binding protein;Eps8 SH3 domain-binding protein;Eps8-binding protein;Hssh3bp1;Interactor protein AblBP4;NAP1;Nap1 binding protein;Nap1-binding protein;Nap1BP;Spectrin SH3 domain binding protein 1;Spectrin SH3 domain-binding protein 1;SSH3BP
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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