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SKU: E-AB-12884_120μL-ES
AKAP12 Polyclonal Antibody, 120 μL
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.4 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Neuroscience;Signal Transduction
Species Reactivity:Human
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Target Synonym:A kinase (PRKA) anchor protein (gravin) 12;A kinase Anchor Protein 12;A kinase anchor protein 250kDa;A-kinase anchor protein 12;A-kinase anchor protein 250 kDa;AKA12;AKAP 12;AKAP 250;AKAP-12;Akap12;AKAP250;DKFZp686M0430;DKFZp686O0331;FLJ20945;FLJ97621;Gercelin;Gravin;Kinase scaffold protein gravin;Myasthenia gravis autoantigen;Myasthenia gravis autoantigen gravin;OTTHUMP00000017426;OTTHUMP00000017427;Src-Suppressed C Kinase Substrate;Srcs5;SSeCKS;Tsga12
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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