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SKU: E-AB-40478_100μL-ES
Angiotensinogen Polyclonal Antibody, 100 μL
Angiotensinogen is a precursor of angiotensin II (Ang II),is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product,angiotensin I,is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension,and can cause renal tubular dysgenesis,a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation,and inflammatory bowel disease.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Calculated Molecular Weight:52 kDa
Observed Molecular Weight:52 kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:52 kDa
Dilution:WB 1:2000-1:5000;IHC 1:100-1:300
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Application:WB;IHC
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Research Areas:Cancer;Cardiovascular;Metabolism;Signal Transduction
Species Reactivity:Mouse;Rat
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Target Synonym:Aangiotensinogen (serpin peptidase inhibitor clade A member 8); AGT; AI265500; Alpha 1 antiproteinase antitrypsin; Ang; Ang I; Ang II; Ang III; AngII; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-3; Angiotensinogen (PAT); Angiotensinogen; ANGT; ANHU; ANRT; AT-2; AT-II; Des-Asp[1]-angiotensin II; PAT; Pre angiotensinogen; Serine (or cysteine) proteinase inhibitor; Serpin A8; Serpin peptidase inhibitor clade A member 8; SERPINA8
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Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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