BT LAB

SKU: BT-AP00662-50ul

ASC Polyclonal Antibody, 50ul

PYCARD encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein (PYD and CARD domain containing) is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for PYCARD.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Technical Specifications

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Application:WB, IHC-p, IF, ELISA

Detection Target:PYCARD

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Research Areas:Cell Biology

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Reactivity:Human, Mouse, Rat

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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