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SKU: E-AB-52456_20μL-ES
ATXN3 Polyclonal Antibody, 20 μL
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:40-1:200
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Application:IHC
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Neuroscience
Species Reactivity:Human
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Target Synonym:AT3;Ataxin 3;ataxin 3 variant h;ataxin 3 variant m;ataxin 3 variant ref;Ataxin-3;ATX3;ATX3;ATXN3;EC 3.4.22.;JOS;Josephin;Machado Joseph disease (spinocerebellar ataxia 3;olivopontocerebellar ataxia 3;autosomal dominant;ataxin 3);Machado Joseph disease;Machado Joseph disease protein 1;Machado-Joseph disease protein 1;Machado-Joseph disease protein 1 homolog;MJD;MJD gene;MJD1;Olivopontocerebellar ataxia 3;OTTHUMP00000221583;OTTHUMP00000221585;OTTHUMP00000221586;OTTHUMP00000221587;OTTHUMP00000231995;OTTHUMP00000231997;Rsca3;SCA3;SCA3 gene;Spinocerebellar ataxia type 3 protein
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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