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SKU: E-AB-52275_60μL-ES
ATXN7L3 Polyclonal Antibody, 60 μL
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Calculated Molecular Weight:39 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:39 kDa
Dilution:WB 1:500-1:2000;IHC 1:25-1:100
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Application:WB;IHC
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Research Areas:Cell Biology;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse
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Target Synonym:AT7L3;Ataxin 7 like 3;Ataxin 7 like protein 3;Ataxin-7-like protein 3;atxn7l3;SAGA associated factor 11 homolog;SAGA-associated factor 11 homolog
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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