SKU: E-AB-67774_200μL-ES

BAP1 Polyclonal Antibody, 200 μL

This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Technical Specifications

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Concentration:1mg/mL

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Calculated Molecular Weight:80kDa

Observed Molecular Weight:80kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:80kDa

Dilution:WB 1:500-1:2000;IHC 1:50-1:200;IF 1:50-1:200

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Features and Capabilities

Application:WB;IHC;IF

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Research Areas:Cancer; Cell Biology; Epigenetics and Nuclear Signaling

Species Reactivity:Human; Mouse; Rat

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Target Synonym:BAP1;HUCEP-13;UCHL2;hucep-6

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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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