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SKU: E-AB-92375_120μL-ES
CD146/MCAM Polyclonal Antibody, 120 μL
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:57kDa/71kDa
Observed Molecular Weight:120KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:57kDa/71kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Cardiovascular;Immunology;Signal Transduction;Stem Cells
Species Reactivity:Human;Rat
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Target Synonym:MCAM; CD146; MUC18; cell surface glycoprotein MUC18
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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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