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SKU: E-AB-62039_60μL-ES
CHEK1 Polyclonal Antibody, 60 μL
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:43kDa/50kDa/54kDa
Observed Molecular Weight:54kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:43kDa/50kDa/54kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200;IF 1:50-1:200
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Application:WB;IHC;IF
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse;Rat
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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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