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SKU: E-AB-92600_60μL-ES
CLASP2 Polyclonal Antibody, 60 μL
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:46kDa/141kDa/165kDa
Observed Molecular Weight:141kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:46kDa/141kDa/165kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cell Biology;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:CLASP2
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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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