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SKU: E-AB-90808_200μL-ES
COQ6 Polyclonal Antibody, 200 μL
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1mg/mL
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Calculated Molecular Weight:42kDa/48kDa/50kDa
Observed Molecular Weight:51kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:42kDa/48kDa/50kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Neuroscience;Metabolism
Species Reactivity:Human;Mouse
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Target Synonym:COQ6;CGI-10;CGI10;COQ10D6;coenzyme Q6
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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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