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SKU: E-AB-52144_120μL-ES
COX7A2L Polyclonal Antibody, 120 μL
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:30-1:150
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Application:IHC
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Research Areas:Cancer;Metabolism;Signal transduction
Species Reactivity:Human;Mouse
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Target Synonym:COX7a related protein;COX7a-related protein;COX7A2L;COX7AR;COX7R;COX7RP;Cytochrome c oxidase subunit 7A-related protein;cytochrome c oxidase subunit 7A-related protein; mitochondrial;Cytochrome c oxidase subunit 7A2 like;cytochrome c oxidase subunit VII-related protein;cytochrome c oxidase subunit VIIa polypeptide 2 like;Cytochrome c oxidase subunit VIIa related protein; mitochondrial;Cytochrome c oxidase subunit VIIa-related protein;EB1;Estrogen receptor binding CpG island;mitochondrial;SIG81
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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