SKU: E-AB-16677_120μL-ES

CYP1A2 Polyclonal Antibody, 120 μL

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:0.3 mg/mL

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Calculated Molecular Weight:58kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:58kDa

Dilution:WB 1:200-1:1000;IHC 1:50-1:200

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Features and Capabilities

Application:WB;IHC

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Research Areas:Cancer;Cardiovascular;Metabolism;Signal transduction

Species Reactivity:Human

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Target Synonym:Aryl hydrocarbon hydroxylase;CP 12;CP12;CP1A2;CYP1A2;CYPIA2;Cytochrome P(3)450;Cytochrome P450 1A2;Cytochrome P450 4;Cytochrome P450 family 1 polypeptide 2;Cytochrome P450 family 1 subfamily A polypeptide 2;Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2;Cytochrome P450-P3;Cytochrome P4501A2;Dioxin inducable P3 450;Flavoprotein linked monooxygenase;Microsomal monooxygenase;P(3)450;P3 450;P450 4;P450 form 4;P450 P3;P450(PA);Xenobiotic monooxygenase

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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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