SKU: E-AB-70333_60μL-ES

EGFR Polyclonal Antibody, 60 μL

EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Technical Specifications

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Concentration:1.35 mg/mL

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Calculated Molecular Weight:134kDa

Observed Molecular Weight:175kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:134kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cancer; Signal Transduction

Species Reactivity:Human; Mouse; Rat

Reactivity:

Target Synonym:Avian erythroblastic leukemia viral (v erb b) oncogene homolog;Cell growth inhibiting protein 40;Cell proliferation inducing protein 61;EGF R;EGFR;EGFR;Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog);Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian);Epidermal growth factor receptor;erb-b2 receptor tyrosine kinase 1;ERBB;ERBB1;Errp;HER1;mENA;NISBD2;Oncogen ERBB;PIG61;Proto-oncogene c-ErbB-1;Receptor tyrosine protein kinase ErbB 1;Receptor tyrosine-protein kinase ErbB-1;SA7;Species antigen 7;Urogastrone;v-erb-b Avian erythroblastic leukemia viral oncogen homolog;wa2;Wa5

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Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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