BT LAB

SKU: BT-AP08984-100ul

ERR3 Polyclonal Antibody, 100ul

This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expre

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, ELISA

Detection Target:ESRRG

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Research Areas:Cancer; Epigenetics and nuclear signaling; Signal transduction

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Reactivity:Human, Rat, Mouse

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

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