SKU: E-AB-91407_60μL-ES

F7 Polyclonal Antibody, 60 μL

This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:49kDa/51kDa

Observed Molecular Weight:46kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:49kDa/51kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cancer;Cardiovascular

Species Reactivity:Human;Mouse;Rat

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Target Synonym:F7;SPCA

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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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