BT LAB

SKU: BT-AP03123-100ul

Factor IX Polyclonal Antibody, 100ul

F9(coagulation factor IX) encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of F9, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Application:WB, ELISA

Detection Target:F9

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Research Areas:Cardiovascular

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Reactivity:Human, Mouse, Rat

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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