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SKU: E-AB-52260_200μL-ES
FNDC3B Polyclonal Antibody, 200 μL
Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:30-1:150
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Application:IHC
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Research Areas:Metabolism;Signal transduction;Stem cells
Species Reactivity:Human;Mouse
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Target Synonym:DKFZp686D14170 ;DKFZp762K137;Factor for adipocyte differentiation 104;FAD104;fibronectin type III domain containing 3B ;FLJ23399;HCV NS5A binding protein 37 ;MGC10002;NS5ABP37;PRO4979;YVTM2421
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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