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SKU: E-AB-31644_120μL-ES
HDAC2 Polyclonal Antibody, 120 μL
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:55kDa
Observed Molecular Weight:55kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:55kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300
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Application:WB;IHC-p
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Research Areas:Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Stem Cells
Species Reactivity:Human;Mouse;Rat;Monkey
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Target Synonym:D10Wsu179e;HD 2;HD2;HDAC 2;Hdac2;HDAC2;Histone deacetylase 2 (HD2);Histone deacetylase 2;OTTHUMP00000017046;OTTHUMP00000227077;OTTHUMP00000227078;RPD3;transcriptional regulator homolog RPD3;YAF1;YY1 associated factor 1;YY1 transcription factor binding protein;Yy1bp
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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