SKU: E-AB-92661_60μL-ES

HEXA Polyclonal Antibody, 60 μL

This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:19kDa/60kDa

Observed Molecular Weight:55KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:19kDa/60kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Neuroscience

Species Reactivity:Human;Mouse;Rat

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Target Synonym:HEXA;TSD

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Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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