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SKU: E-AB-53135_120μL-ES
HORMAD2 Polyclonal Antibody, 120 μL
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:100
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Application:IHC
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Research Areas:Cell Biology
Species Reactivity:Human
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Target Synonym:4930529M09Rik;CT46.2;HORM2;HORMA domain containing 2;HORMA domain-containing protein 2;Hormad2;MGC26710;RP23-329P17.4
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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