BT LAB

SKU: BT-E3037Hu-96T

Human Atp-binding Cassette Sub-family A Member 3, ABCA3 ELISA Kit, 96T

Catalyzes the ATP-dependent transport of phospholipids such as phosphatidylcholine and phosphoglycerol from the cytoplasm into the lumen side of lamellar bodies, in turn participates in the lamellar bodies biogenesis and homeostasis of pulmonary surfactant (PubMed: 16959783, PubMed: 17574245, PubMed: 28887056, PubMed: 31473345, PubMed: 27177387). Transports preferentially phosphatidylcholine containing short acyl chains (PubMed: 27177387). In addition plays a role as an efflux transporter of miltefosine across macrophage membranes and free cholesterol (FC) through intralumenal vesicles by removing FC from the cell as a component of surfactant and protects cells from free cholesterol toxicity (PubMed: 26903515, PubMed: 25817392, PubMed: 27177387).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:10.03ng/L

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Application:ELISA

Detection Target:ABCA3

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Detection Range: 20-3800ng/L

Research Areas:Signal Transduction

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Assay Time:1h 30m

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