BT LAB

SKU: BT-E5064Hu-96T

Human Coiled-Coil Domain-containing Protein 134, CCDC134 ELISA Kit , 96T

In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function (PubMed: 25125657). Enhances cytotoxic anti-tumor activity of CD8(+) T cells (PubMed: 25125657). May inhibit ERK and JNK signaling activity (PubMed: 18087676, PubMed: 23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed: 23070808). In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity. May inhibit TADA2A-mediated TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:0.021ng/ml

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Application:ELISA

Detection Target:CCDC134

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Detection Range: 0.05-20ng/ml

Research Areas:Others

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Assay Time:1h 30m

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