BT LAB

SKU: BT-E3631Hu-96T

Human Cubilin, CUBN ELISA Kit, 96T

Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake (PubMed: 9572993, PubMed: 10371504, PubMed: 11717447, PubMed: 11606717, PubMed: 14576052). Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex (PubMed: 9572993, PubMed: 14576052). Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium (PubMed: 9572993). Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:0.28ng/ml

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Features and Capabilities

Application:ELISA

Detection Target:CUBN

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Detection Range: 0.5-150ng/ml

Research Areas:Signal Transduction

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Test Principle:Sandwich

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Assay Time:1h 30m

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