BT LAB

SKU: BT-E2283Hu-96T

Human Cyclin T1, CCNT1 ELISA Kit, 96T

Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). (Microbial infection) In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:4.96ng/L

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Application:ELISA

Detection Target:CCNT1

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Detection Range: 10-2000ng/L

Research Areas:Microbiology

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Reactivity:Human

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Assay Time:1h 30m

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