BT LAB

SKU: BT-E3287Hu-96T

Human Estrogen Receptor Beta, ER-beta ELISA Kit, 96T

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed: 20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:0.026ng/ml

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Features and Capabilities

Application:ELISA

Detection Target:ESR2

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Detection Range: 0.05-20ng/ml

Research Areas:Others

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Assay Time:1h 30m

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