BT LAB

SKU: BT-E2711Hu-96T

Human General Transcription Factor Iih Subunit 1, GTF2H1 ELISA Kit, 96T

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:5.54ng/L

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Application:ELISA

Detection Target:GTF2H1

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Detection Range: 10-2000ng/L

Research Areas:Epigenetics and Nuclear Signaling

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Test Principle:Sandwich

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Assay Time:1h 30m

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