BT LAB

SKU: BT-E5896Hu-96T

Human Polycystin-1, PKD1 ELISA Kit , 96T

Component of a heteromeric calcium-permeable ion Channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed: 27214281). Both PKD1 and PKD2 are required for Channel activity (PubMed: 27214281). Involved in renal tubulogenesis (PubMed: 12482949). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-Channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:8.96ng/L

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Application:ELISA

Detection Target:PKD1

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Detection Range: 20-4500ng/L

Research Areas:Others

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Reactivity:Human

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Test Principle:Sandwich

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Assay Time:1h 30m

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