BT LAB

SKU: BT-E4170hu-96T

Human Prestin, PRES ELISA Kit, 96T

Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ. Prestin is a bidirectional voltage-to-force converter, it can operate at microsecond rates. It uses cytoplasmic anions as extrinsic voltage sensors, probably chloride and bicarbonate. After binding to a site with millimolar affinity, these anions are translocated across the membrane in response to changes in the transmembrane voltage. They move towards the extracellular surface following hyperpolarization, and towards the cytoplasmic side in response to depolarization. As a consequence, this translocation triggers conformational changes in the protein that ultimately alter its surface area in the plane of the plasma membrane. The area decreases when the anion is near the cytoplasmic face of the membrane (short state), and increases when the ion has crossed the membrane to the outer surface (long state). So, it acts as an incomplete transporter. It swings anions across the membrane, but does not allow these anions to dissociate and escape to the extracellular space. Salicylate, an inhibitor of outer hair cell motility, acts as competitive antagonist at the prestin anion-binding site (By similarity).

€370,98 EUR
€370,98 EUR
2-4 weeks
Hassle-Free Warranty
Safe & Secure Payment
Livetime Tech Support
  • Specification
  • Downloads
  • Reviews
€370,98
ADD TO CART
ADD TO CART

Product Specification

Basic Information

Brands:BT LAB

Model Number:

Place of Origin:China

Warranty:

Safety Performance:

Protection Class:

Sterile Status:

Reconstitution:

Shipping:

Battery:

Battery Service Life:

Component:

Technical Specifications

Capacity:

Concentration:

Dimension [D×W×H]:

Diameter:

Length:

Width:

High:

Volume:

Volume Range:

Speed:

Speed Range:

Max.Speed:

Max. RCF:

Temperature Range:

Operating Temperature Range:

Permissible Ambient Temperature :

Permissible Relative Humidity:

Input voltage:

Power Requirements:

Voltage/Frequency:

Sensitivity:4.87pg/ml

Specificity:

Precision:

Speed Accuracy:

Volume Accuracy:

Particle Size:

Pore Size:

Binding Capacity:

Calculated Molecular Weight:

Observed Molecular Weight:

Purity:

Shelf Life:

Storage:2-8ºC

Random Error:

Acceleration/Braking time:

Aspiration Speed:

Calculated Molecular Weight:

Dilution:

Driving Motor DC motor:

Em:

Ex:

Endotoxin:

Flow rate [liquid]:

Features and Capabilities

Application:ELISA

Detection Target:SLC26A5

Detection Type:

Detection Range: 10-3000pg/ml

Research Areas:Neuroscience

Species Reactivity:

Reactivity:Human

Target Synonym:

Test Principle:Sandwich

Quantitative/Qualitative :

Result Type:

Materials :

Assay Time:1h 30m

Autoclave component:

Available Rotor Adapters:

Binding Capacity:

Bio-activity:

Bottom Shape:

Bottom Type:

Buffer:

Cap Color:

Clonality:

Conjugation:

Coupled Ligand:

Cover Type:

Detection Instrument :

Dispensing Speed:

Display:

Form:

Formulation:

Graduation:

Growth Area:

Download File