BT LAB

SKU: BT-E4717Hu-96T

Human Raftlin, RFTN1 ELISA Kit, 96T

Involved in protein trafficking via association with clathrin and AP2 complex (PubMed: 27022195, PubMed: 21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed: 27022195, PubMed: 21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed: 12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed: 12805216).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:0.41ng/ml

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Features and Capabilities

Application:ELISA

Detection Target:RFTN1

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Detection Range: 0.5-40ng/ml

Research Areas:Tags & Cell Markers

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Assay Time:1h 30m

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