BT LAB

SKU: BT-E0374Hu-96T

Human Toll-like Receptor 5, TLR5 ELISA Kit , 96T

Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed: 11323673, PubMed: 18490781). Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota (PubMed: 29934223). Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response (PubMed: 20855887, PubMed: 11489966). Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life (By similarity).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Features and Capabilities

Application:ELISA

Detection Target:TLR5

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Detection Range: 0.1-40ng/ml

Research Areas:Immunology

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Assay Time:1h 30m

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