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SKU: E-AB-52949_60μL-ES
IFT57 Polyclonal Antibody, 60 μL
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:300
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Application:IHC
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Research Areas:Cancer;Neuroscience
Species Reactivity:Human;Mouse
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Target Synonym:CDNA FLJ10147 fis clone HEMBA1003369;Dermal papilla derived protein 8;Dermal papilla-derived protein 8;DERP 8;DERP8;Esrrbl 1;Esrrbl1;ESRRBL1 protein;Estrogen related receptor beta like 1;Estrogen related receptor beta like protein 1;Estrogen-related receptor beta-like protein 1;FLJ10147;Hip1 Interacting protein;HIP1 interacting protein HIPPI;Hip1 protein interactor;HIP1-interacting protein;HIPPI;Huntingtin interacting protein 1 interacting protein;Huntingtin interacting protein 1 protein interactor;IFT 57;ift57;IFT57;Intraflagellar transport 57 homolog (Chlamydomonas);Intraflagellar transport 57 homolog;Intraflagellar transport protein 57 homolog;MHS4R2;Vestrogen related receptor beta like 1
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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