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SKU: E-AB-52510_60μL-ES
IL6ST Polyclonal Antibody, 60 μL
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:30-1:150
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Application:IHC
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Research Areas:Cancer;Cell Biology;Cardiovascular;Immunology;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:CD130;CD130 antigen;CDw130;gp130;GP130 RAPS;IL 6R beta;IL-6 receptor subunit beta;IL-6R subunit beta;IL-6R-beta;IL-6RB;IL6 ST;IL6RB;IL6ST;Interleukin 6 receptor subunit beta;Interleukin receptor beta chain;Interleukin-6 receptor subunit beta;Interleukin-6 signal transducer;Membrane glycoprotein 130;Membrane glycoprotein gp130;Oncostatin M receptor;Oncostatin M receptor alpha subunit;Oncostatin-M receptor subunit alpha
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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