BT LAB

SKU: BT-AP04704-50ul

JMY Polyclonal Antibody, 50ul

JMY is a Protein Coding gene. Junction-mediating and -regulatory protein acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location. Among its related pathways are Gene Expression and Direct p53 effectors. Gene Ontology (GO) annotations related to this gene include actin binding and transcription coactivator activity. An important paralog of this gene is WHAMM.

€162,00 EUR
€162,00 EUR
2-4 weeks
Hassle-Free Warranty
Safe & Secure Payment
Livetime Tech Support
  • Specification
  • Downloads
  • Reviews
€162,00
ADD TO CART
ADD TO CART

Product Specification

Basic Information

Brands:BT LAB

Model Number:

Place of Origin:China

Warranty:

Safety Performance:

Protection Class:

Sterile Status:

Reconstitution:

Shipping:

Battery:

Battery Service Life:

Component:

Technical Specifications

Capacity:

Concentration:1 mg/ml

Dimension [D×W×H]:

Diameter:

Length:

Width:

High:

Volume:

Volume Range:

Speed:

Speed Range:

Max.Speed:

Max. RCF:

Temperature Range:

Operating Temperature Range:

Permissible Ambient Temperature :

Permissible Relative Humidity:

Input voltage:

Power Requirements:

Voltage/Frequency:

Sensitivity:

Specificity:

Precision:

Speed Accuracy:

Volume Accuracy:

Particle Size:

Pore Size:

Binding Capacity:

Calculated Molecular Weight:

Observed Molecular Weight:

Purity:

Shelf Life:

Storage:-20°C for 1 year

Random Error:

Acceleration/Braking time:

Aspiration Speed:

Calculated Molecular Weight:

Dilution:

Driving Motor DC motor:

Em:

Ex:

Endotoxin:

Flow rate [liquid]:

Features and Capabilities

Application:WB, ELISA

Detection Target:JMY

Detection Type:

Detection Range:

Research Areas:Cell Biology

Species Reactivity:

Reactivity:Human, Mouse

Target Synonym:

Test Principle:

Quantitative/Qualitative :

Result Type:

Materials :

Assay Time:

Autoclave component:

Available Rotor Adapters:

Binding Capacity:

Bio-activity:

Bottom Shape:

Bottom Type:

Buffer:

Cap Color:

Clonality:Polyclonal

Conjugation:

Coupled Ligand:

Cover Type:

Detection Instrument :

Dispensing Speed:

Display:

Form:

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Graduation:

Growth Area:

Download File