SKU: E-AB-52818_120μL-ES

JPT1 Polyclonal Antibody, 120 μL

Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:30-1:150

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Application:IHC

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Research Areas:Cell Biology

Species Reactivity:Human;Mouse;Rat

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Target Synonym:Androgen regulated protein 2;Androgen-regulated protein 2;ARM2;Hematological and neurological expressed 1;Hematological and neurological expressed 1 protein;HN1;HN1;HN1A

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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

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