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SKU: E-AB-16544_200μL-ES
KCNQ4 Polyclonal Antibody, 200 μL
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.9 mg/mL
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Calculated Molecular Weight:77kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:77kDa
Dilution:WB 1:200-1:1000;IHC 1:50-1:200
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Application:WB;IHC
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Research Areas:Cancer;Neuroscience
Species Reactivity:Human;Mouse
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Target Synonym:DFNA 2;DFNA2;KCNQ 4;Kcnq4;KCNQ4;KQT like 4;KQT-like 4;KV7.4;Potassium channel KQT like 4;Potassium channel subunit alpha KvLQT4;Potassium voltage gated channel KQT like protein 4;Potassium voltage gated channel KQT like subfamily member 4;Potassium voltage gated channel subfamily KQT member 4;Potassium voltage-gated channel subfamily KQT member 4;Voltage gated potassium channel subunit Kv7.4;Voltage-gated potassium channel subunit Kv7.4
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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