SKU: E-AB-92357_200μL-ES

(KO Validated) FH Polyclonal Antibody, 200 μL

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:50kDa/54kDa

Observed Molecular Weight:49KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:50kDa/54kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cancer;Metabolism;Signal Transduction

Species Reactivity:Human

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Target Synonym:FH; FMRD; HLRCC; LRCC; MCL; MCUL1; fumarate hydratase

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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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