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SKU: E-AB-13334_200μL-ES
KPNB1 Polyclonal Antibody, 200 μL
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Signal Transduction;Tags and Cell Markers
Species Reactivity:Human;Mouse;Rat
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Target Synonym:IMB 1;IMB1;IMB1;Impnb;Importin 90;Importin beta 1;Importin beta 1 subunit;Importin subunit beta-1;Importin-90;IPOB;Karyopherin beta 1;Karyopherin beta 1 subunit;Karyopherin subunit beta-1;KPNB 1;Kpnb1;MGC2155;MGC2156;MGC2157;NTF 97;NTF97;Nuclear factor P97;Pore targeting complex 97 kDa subunit;PTAC97
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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