SKU: E-AB-91223_60μL-ES

MAP3K8 Polyclonal Antibody, 60 μL

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Technical Specifications

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Concentration:1mg/mL

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Calculated Molecular Weight:49kDa/52kDa

Observed Molecular Weight:52KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:49kDa/52kDa

Dilution:WB 1:500-1:2000

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Features and Capabilities

Application:WB

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Research Areas:Cancer;Signal Transduction

Species Reactivity:Human;Mouse;Rat

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Target Synonym:MAP3K8;AURA2;COT;EST;ESTF;MEKK8;TPL2;Tpl-2;c-COT

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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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