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SKU: E-AB-52157_120μL-ES
MAPK8 Polyclonal Antibody, 120 μL
MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1,PRKM8,SAPK1,SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73,mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Calculated Molecular Weight:48 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:48 kDa
Dilution:WB 1:1000-1:5000
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Application:WB
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Research Areas:Cancer;Immunology;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:AI849689;c Jun N terminal kinase 1;C-JUN kinase 1;c-Jun N-terminal kinase 1;EC 2.7.11.24;JNK 1;JNK;JNK-46;JNK1A2;JNK21B1/2;MAP kinase 8;MAPK 8;mapk8;Mitogen activated protein kinase 8;Mitogen-activated protein kinase 8;MK08;p54 gamma;Prkm8;Protein kinase JNK1;Protein kinase;mitogen-activated;8;SAPK 1;SAPK gamma;SAPK1;Stress-activated protein kinase 1;Stress-activated protein kinase JNK1
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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