BT LAB

SKU: BT-AP05256-100ul

MBD3 Polyclonal Antibody, 100ul

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MBD3 belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). Methyl-CpG-binding domain protein 3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, ELISA

Detection Target:MBD3

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Research Areas:Epigenetics and Nuclear Signaling

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Reactivity:Human, Mouse

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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