SKU: E-AB-68412_120μL-ES

MLH3 Polyclonal Antibody, 120 μL

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Technical Specifications

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Concentration:1 mg/mL

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Calculated Molecular Weight:161kDa/163kDa

Observed Molecular Weight:164kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:161kDa/163kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Epigenetics and Nuclear Signaling

Species Reactivity:Human

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Target Synonym:MLH3;HNPCC7

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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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