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SKU: E-AB-12571_60μL-ES
MMP25 Polyclonal Antibody, 60 μL
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.5 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Cell Biology;Signal Transduction
Species Reactivity:Human
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Target Synonym:Leukolysin;matrix metallopeptidase 25;matrix metallopeptidase like 1;matrix metalloproteinase 20;Matrix Metalloproteinase 25;Matrix metalloproteinase 25 precursor;Matrix metalloproteinase-25;Membrane type 6 Matrix Metalloproteinase;Membrane type Matrix Metalloproteinase 6;Membrane-type matrix metalloproteinase 6;Membrane-type-6 matrix metalloproteinase;MMP 25;MMP-25;MMP20;MMP20A;MMP25;MMP25;MMPL1;MT-MMP 6;MT6-MMP;MT6MMP;MTMMP6
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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