SKU: E-AB-91420_200μL-ES

MTA1 Polyclonal Antibody, 200 μL

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:49kDa/79kDa/80kDa

Observed Molecular Weight:78-82KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:49kDa/79kDa/80kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Epigenetics and Nuclear Signaling

Species Reactivity:Human;Mouse

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Target Synonym:MTA1

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Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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