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SKU: E-AB-32226_60μL-ES
NFκB-p105/p50 Polyclonal Antibody, 60 μL
NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:105kDa
Observed Molecular Weight:50,110kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:105kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000
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Application:WB;IHC-p;IF
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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction
Species Reactivity:Human;Mouse
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Target Synonym:DKFZp686C01211;DNA binding factor KBF1;DNA binding factor KBF1 EBP1;DNA-binding factor KBF1;EBP 1;EBP-1;EBP1;KBF1;MGC54151;nf b;NF kappa B;NF kappaB;NF kappabeta;NF kB1;NFkappaB;NFKB 1;NFKB p105;NFKB p50;Nfkb1;NFKB1;Nuclear factor kappa B DNA binding subunit;Nuclear factor kappa-B;subunit 1;Nuclear factor NF kappa B p105 subunit;Nuclear factor NF kappa B p50 subunit;Nuclear factor NF-kappa-B p50 subunit;Nuclear factor of kappa light chain gene enhancer in B cells 1;Nuclear factor of kappa light polypeptide gene enhancer in B cells 1;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1;p105;p50;p84/NF-kappa-B1 p98;Transcription factor NFKB1
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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