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SKU: E-AB-15504_120μL-ES
NPR1 Polyclonal Antibody, 120 μL
Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.4 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:25-1:100
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Application:IHC
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Research Areas:Cancer;Cardiovascular;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:ANP-A;ANPa;ANPR-A;ANPRA;ANPRA;Atrial natriuretic peptide A type receptor;Atrial natriuretic peptide receptor 1;Atrial natriuretic peptide receptor A;Atrial natriuretic peptide receptor type A;Atrionatriuretic peptide receptor A;GC A;GC-A;Guanylate cyclase A;Guanylate cyclase;GUC2A;GUCY2A;Natriuretic peptide A type receptor;Natriuretic peptide receptor A/guanylate cyclase A;NPR-A;NPR1;NPRA
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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