BT LAB

SKU: BT-AP07431-50ul

p53(Phospho Ser392) Polyclonal Antibody, 50ul

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Technical Specifications

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, IHC-p, IF, ICC, ELISA

Detection Target:TP53

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Research Areas:Epigenetics and nuclear signaling; Cancer; Cell biology

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Reactivity:Human, Monkey

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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