BT LAB

SKU: BT-AP11831-50ul

PCDG1 Rabbit Polyclonal Antibody, 50ul

This gene is a member of the protocadherin gamma gene cluster| one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization| suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes| subfamily B contains 7 genes and 2 pseudogenes| and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large| variable region exons are followed by a constant region| containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region| which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Application:WB

Detection Target:PCDHGA1

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Research Areas:Neuroscience; Signal transduction

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Reactivity:Human, Rat, Mouse

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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