- Specification
- Downloads
- Reviews
€560,00
ADD TO CART
SKU: E-AB-91960_60μL-ES
PDCD1LG2 Polyclonal Antibody, 60 μL
Programmed Death Ligand 2 (PD-L2), also known as B7-DC and butyrophilin-like protein, is a member of the B7 family of proteins that provide signals for regulating T-cell activation and tolerance .PD-L2 is expressed on dendritic cells, subsets of activated CD4+ and CD8+ T cells, and memory B cells that differentiate into plasma cells. At inflammatory sites such as rheumatoid arthritis, allergen exposure, and virus infection, PD-L2 is up-regulated on synoviocytes, infiltrating macrophages, dendritic cells, and airway epithelial cells. PD-L2, along with B7-H1/PD-L1, binds to T cell PD-1 where it promotes IFN-gamma production and CD40 Ligand up-regulation while inhibiting IL-4 production. In addition, PD-L2 binds to RGM-B on macrophages and alveolar epithelial cells, supporting respiratory immune tolerance. In asthma, PD-L2 suppresses IL-5 and IL-13 production, promotes IL-12 production by dendritic cells, and supports allergen-induced airway hyper-responsiveness and mucus production.
- Regular price
- €560,00 EUR
- Sale price
- €560,00 EUR
- Regular price
-
ADD TO CART
Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Battery:
Battery Service Life:
Component:
Technical Specifications
Capacity:
Concentration:1mg/mL
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:
Observed Molecular Weight:45-60KDa
Purity:
Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:
Dilution:WB 1:500-1:2000;IF 1:50-1:200
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Features and Capabilities
Application:WB;IF
Detection Target:
Detection Type:
Detection Range:
Research Areas:Immunology
Species Reactivity:Human;Mouse;Rat
Reactivity:
Target Synonym:B7DC;Btdc;CD273;PD-L2;PDCD1L2;PDL2;bA574F11.2;PDCD1LG2
Test Principle:
Quantitative/Qualitative :
Result Type:
Materials :
Assay Time:
Autoclave component:
Available Rotor Adapters:
Binding Capacity:
Bio-activity:
Bottom Shape:
Bottom Type:
Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.
Cap Color:
Clonality:Polyclonal
Conjugation:Unconjugated
Coupled Ligand:
Cover Type:
Detection Instrument :
Dispensing Speed:
Display:
Form:
Formulation:
Graduation:
Growth Area:
Powered by Bioz